Pesquisa | SciELO

Resumen Introducción: las clasificaciones de pie diabético (PD) son una herramienta que tienen el objetivo de mejorar la comunicación entre los profesionales, la referencia y contrarreferencia; proporcionar un pronóstico; ayudar en la valoración de las lesiones, y contribuir con fines estadísticos. Objetivos: describir las características de los pacientes que se presentaron al consultorio o a la guardia con un PD durante un período de 3 meses, determinar el riesgo según cinco clasificaciones (Texas, IDSA, San Elián, WIfI y SINBAD) y evaluar su evolución a 6 meses en relación con el grado de gravedad determinada por cada clasificación. Materiales y métodos: se analizaron 312 pacientes de 15 instituciones en Argentina. Para el análisis se utilizó la calculadora de clasificaciones de pie diabético/score de riesgo del Comité de Pie Diabético de la Sociedad Argentina de Diabetes. Resultados: el 43% de los pacientes (n=133) requirió internación al momento de la primera consulta y el 61% (n=189) había consultado previamente. El porcentaje de amputación mayor total fue de 8,33% (IC 95%; 5,5-11,9) (n=26) y el de amputación menor de 29,17% (IC 95%; 24,2-34,6) (n=91). A los 6 meses, el porcentaje de muerte fue de 4,49% (IC 95%; 2,5-7,4) (n=14), el 24,3% (IC 95%;19,6-29,5) presentaba la herida aún abierta (n=76), el 58,0% (IC 95%; 52,3-66,5) (n=181) cicatrizó y el 7,37% se perdió del seguimiento (n=23). Las clasificaciones de San Elián y WIfI se relacionaron con amputación mayor, cicatrización y muerte. En relación a la clasificación de Texas, el 49% de los pacientes presentó herida penetrante a hueso o articulación (Texas 3), con o sin infección. El 65,3% de las amputaciones mayores y el 78,6% de las muertes se produjeron en pacientes con isquemia. El punto de corte de San Elián para amputación mayor fue 20. Conclusiones: conocer los datos locales permite organizar los recursos para mejorar la atención de los pacientes.

Abstract Introduction: the classifications of diabetic foot (DF) are a tool that aims to improve communication between professionals, referral and counter-referral, provide a prognosis, help in the assessment of lesions, and contribute to statistical purposes. Objectives: to describe the characteristics of patients who presented to the clinic or emergency department with DF over a period of 3 months, determine the risk according to 5 classifications (Texas, IDSA, SEWSS, WIfI, and SINBAD), and evaluate their evolution at 6 months in relation to the severity degree determined by each classification. Materials and methods: 312 patients from 15 institutions in Argentina were analyzed. The Diabetic Foot Classification Calculator/Risk Score from the Diabetic Foot Committee of the Argentina Argentina Diabetes Society was used for the analysis. Results: 43% of patients (n=133) required hospitalization at the time of the first consultation and 61% (n=189) had previously consulted. The total major amputation percentage was 8.33% (95%CI; 5.5-11.9) (n=26), and the minor amputation percentage was 29.17% (95% CI; 24.2-34.6) (n=91). At 6 months, the death rate was 4.49% (95% CI; 2.5-7.4) (n=14), 24.3% (95% CI; 19.629.5) had an open wound (n=76), 58.0% (95% CI; 52.3-66.5) (n=181) had healed, and 7.37% were lost to follow-up (n=23). The SEWSS and WIfI classifications were related to major amputation, healing, and death. Regarding the Texas classification, 49% of patients had a penetrating wound to bone or joint (Texas 3), with or without infection. 65.3% of major amputations and 78.6% of deaths occurred in patients with ischemia. The SEWSS cut-off point for major amputation was 20. Conclusions: knowing local data allows organizing resources to improve patient care.

Travestis, transgender women and young MSM are at high risk for PrEP early loss to follow-up in Rio de Janeiro, Brazil
Facebook Twitter

Outras redes sociais
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Outras redes

Métricas
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

Echeverría-Guevara, Amanda

; Coelho, Lara E.

; Veloso, Valdiléa G.

; Pimenta, Maria C.

; Hoagland, Brenda

; Moreira, Ronaldo I.

; Leite, Iuri

; Jalil, Emília M.

; Cardoso, Sandra W.

; Torres, Thiago S.

; Grinsztejn, Beatriz

Brazilian Journal of Infectious Diseases

Métricas do periódico
- Sobre o periódico
- SciELO Analytics

2023, Volume 27 Nº 1 elocation 102733

Resumo: En | Texto: En | PDF: En

Abstract Introduction Oral pre-exposure prophylaxis (PrEP) with emtricitabine/tenofovir (FTC/TDF) is highly effective in preventing HIV infection. This study aimed to identify factors associated with PrEP early loss to follow-up (ELFU) among gay, bisexual and other men who have sex with men (MSM), travestis and transgender women (TGW). Methodology This was a prospective cohort study evaluating TGW and MSM who initiated PrEP at the Evandro Chagas National Institute of Infectious Diseases (INI-Fiocruz) from 2014 to 2020. ELFU was defined as not returning for a PrEP visit within 180 days after first dispensation. Exposure variables included age, gender, race, education, transactional sex, condomless anal intercourse [CAI] (both in the past six months), binge drinking and substance use (both in past three months) and syphilis diagnosis at baseline. Multilevel logistic regression models with random intercepts and fixed slopes were used to identify factors associated with ELFU accounting for clustering of participants according to their PrEP initiation study/context (PrEP Brasil, PrEParadas, ImPrEP and PrEP SUS). Results Among 1,463 participants, the median age was 29 years (interquartile range 24-36), 83% self-identified as MSM, 17% as TGW, 24% were black, 37% mixed-black/pardo and 30% had < 12 years of education. Fifteen percent reported transactional sex, 59% reported CAI, 67% binge drinking, 33% substance use, and 15% had a syphilis diagnosis. Overall, 137 participants (9.7%) had ELFU. Younger age (18-24 years) (adjusted odds ratio [aOR] 1.9, 95%CI:1.2-3.2), TGW (aOR 2.8, 95%CI:1.6-4.8) and education < 12 years (aOR 1.9, 95%CI:1.2-2.9) were associated with greater odds of ELFU. Conclusion TGW, young individuals and those with lower education were at higher risk of PrEP ELFU. Our results suggest that the development of specific strategies targeting these populations should be a priority, through policies that aim to reduce the incidence of HIV infection.

https://doi.org/10.1016/j.bjid.2022.102733

The first case of acute HIV and monkeypox coinfection in Latin America
Facebook Twitter

Outras redes sociais
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Outras redes

Métricas
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

Silva, Mayara Secco Torres

; Santos, Desiree Gomes dos

; Coutinho, Carolina

; Ribeiro, Maria Pia Diniz

; Cardoso, Sandra Wagner

; Veloso, Valdilea Gonçalves

; Grinsztejn, Beatriz

Brazilian Journal of Infectious Diseases

Métricas do periódico
- Sobre o periódico
- SciELO Analytics

2023, Volume 27 Nº 2 elocation 102736

Resumo: En | Texto: En | PDF: En

ABSTRACT Monkeypox (MPX) transmission outside non-endemic countries has been reported since May 2022, rapidly evolving into a multi-country outbreak. A potential role of sexual contact in transmission dynamics, as well as a predominance of anogenitallesions, are remarkable features of current cases. Screening for sexually transmitted infections (STIs) plays an important role in the evaluation of patients with suspected MPX infection. Herein we report the first case of a patient diagnosed with both MPX and acute HIV infection in Latin America. He had no major complications during his clinical course, and antiretroviral therapy was promptly initiated. Diagnosis of acute HIV requires a high level of suspicion and appropriate laboratory investigation. Health practitioners need to consider this diagnosis while evaluating patients with suspected MPX with a recent unprotected sexual contact.

https://doi.org/10.1016/j.bjid.2022.102736

Demografía y COVID-19: Diferenciales sociales y epidemiológicos
Facebook Twitter

Outras redes sociais
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Outras redes

Métricas
- SciELO Analytics

Aja Díaz, Antonio

; Molina Cintra, Matilde de la Caridad

; Trinquete Díaz, Dixie Edith

; Barros Díaz, Otilia Zenaida

; Rodríguez García, Arianna

; Orbea López, Marbelis

; Mora Pérez, Arelis Rosalen

; Araujo González, Rafael

; Farnós Morejón, Alfonso

; Martin Fernández, Consuelo M.

; Dujarric Bermúdez, Gabriela

; Rodríguez Javiqué, Daylin Cecilia

; Terrero Trinquete, Amanda

; Díaz Fernández, Marta

; Benítez Jiménez, Iliana

; Bourzac Macia, Lisset

; Oliveros Domínguez, Eloy Rafael

; Alfonso de Armas, Marisol

; Quintana Llanio, Livia

; Rodríguez Gómez, Grisell

; Castellanos Cabrera, Roxanne

; Bárcenas Alfonso, Jany

; López Bauta, Adis Aymee

; Oroza Fraíz, Teresa

; Cancio-Bello Ayes, Claudia

; Pérez León, Marta Valeria

; Vera Vergara, Vivian

; Llantá Abreu, María del C.

; Lozano Pérez, Teresa Isabel

; Zas Ros, Bárbara

; Gener Serralta, Sandra

; Rivera Fernández, Rosa M.

; Martínez Debs, Leyti

; Quintosa Puebla, Yissel

; Pérez Rodríguez, Nancy

; Oviedo Álvarez, Vivian

; Fernández Lorenzo, Juan Manuel

; Remond Noa, Ricardo

; Torres Reyes, Antonio

; Veranes Miranda, Alejandro

; de la Garma García, Lic. Diana

Anales de la Academia de Ciencias de Cuba

Métricas do periódico
- Sobre o periódico
- SciELO Analytics

Dez 2022, Volume 12 Nº 3 elocation e1115

Resumo: En Es | Texto: En Es | PDF: En | PDF: Es

ABSTRACT Introduction. The behavior of COVID-19 is influenced by diverse social differentials that transcend demographic variables and include morbidity, the conditions of their homes, family dynamics, job performance, gender roles and stereotypes, care tasks, habits, and behaviors of life and consumption, among others. Methods. Statistical and demographic analysis and tools of metric studies of the information were used. Results and Discussion. The research showed the importance of incorporating into the analysis of the behavior of COVID-19 in Cuba the influence of social and epidemiological differentials determined by skin color, marital status, employment status, income levels, types of families, mobility, hygienic environmental conditions, access to health services, among others, which can place populations in greater or lesser conditions of vulnerability. Conclusions: The composition and dynamics of the population together with other social differentials are determinants of the behavior and expression of the pandemic. The crossing of epidemiological factors with the analysis of containment measures and the composition and structure of the affected population allows for the design of health policies that are more adjusted to the needs of the pandemic. Distance psychological counseling makes it possible to identify and deal with situations related to confinement and changes in life routines that affect the mental health of different groups of people.

RESUMEN Introducción. El comportamiento de la COVID-19 está influenciado por diferenciales sociales que trascienden las variables demográficas e incluyen la morbilidad, las condiciones de sus viviendas, las dinámicas familiares, el desempeño laboral, los roles y estereotipos de género, las tareas de cuidado, los hábitos y comportamientos de vida y consumo, entre otros. Métodos. Se empleó el análisis estadístico y demográfico y herramientas de los estudios métricos. Resultados y Discusión. La investigación mostró la importancia de incorporar a los análisis del comportamiento de la COVID-19 en Cuba la influencia de diferenciales sociales y epidemiológicos determinados por el color de la piel, el estado conyugal, la situación laboral, los niveles de ingreso, los tipos de familias, la movilidad, las condiciones higiénico ambientales, el acceso a los servicios de salud, entre otros, que pueden ubicar a las poblaciones en mayores o menores condiciones de vulnerabilidad. Conclusiones, la composición y la dinámica de la población junto a otros diferenciales sociales son determinantes del comportamiento de la pandemia. El cruzamiento de los factores epidemiológicos con el análisis de las medidas de contención y la composición y estructura de población afectada permite diseñar políticas sanitarias más ajustadas a las necesidades de la pandemia. La orientación psicológica a distancia permite identificar y atender situaciones vinculadas al confinamiento y los cambios en las rutinas de vida que afectan la salud mental de diferentes grupos de personas.

Neumotórax espontáneo bilateral en primigestante adolescente, reporte de un caso
Facebook Twitter

Outras redes sociais
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Outras redes

Métricas
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

Beltrán-Acosta, Sandra L.

; Bandera-Barros, Liliana M.

; Torres-Berra, Katerin C.

; Fuentes-Sandoval, María A.

; Ortiz-Ávila, María A.

Revista chilena de obstetricia y ginecología

Métricas do periódico
- Sobre o periódico
- SciELO Analytics

Out 2022, Volume 87 Nº 5 Páginas 360 - 364

Resumo: En Es | Texto: En Es | PDF: En | PDF: Es

Abstract Spontaneous pneumothorax is an extremely rare pathology during pregnancy. It is defined as the presence of air inside the pleural cavity that can mainly generate chest pain and dyspnea. This pathology has a low incidence and prevalence in pregnancy, but a high rate of recurrence with a good prognosis for the mother and the fetus if it is diagnosed early and managed early. It is related to risk factors such as Valsalva maneuvers performed during labor, in addition to comorbidities such as smoking, longilinear biotype, among others, so it is very important to have an adequate history and evaluation of the physical examination. The obstetrician must be attentive to chest pain symptoms associated with dyspnea in pregnant women during labor and delivery, suspect this pathology and take it into account as a differential diagnosis. It is vitally important to have a multidisciplinary management composed of the gynecologist-obstetrician, internist, pulmonologist, neonatologist, including the support of an intensive care unit to avoid maternal-perinatal complications that may be associated with spontaneous pneumothorax.

Resumen El neumotórax espontáneo es una patología extremadamente rara durante la gestación. Se define como la presencia de aire dentro de la cavidad pleural que puede generar principalmente dolor torácico y disnea. Esta patología tiene unas bajas incidencia y prevalencia en el embarazo, pero es relevante por una alta tasa de recurrencia, con un buen pronóstico para la madre y el feto si es tempranamente diagnosticada y oportunamente manejada. Se relaciona con factores de riesgo como las maniobras de Valsalva efectuadas durante el trabajo de parto, además de con comorbilidad como el tabaquismo, y con el biotipo longilíneo, entre otros, por lo que son muy importantes una adecuada anamnesis y la evaluación de la exploración física. El obstetra debe sospecharlo ante la clínica de dolor torácico asociado a disnea en gestantes en el trabajo de parto y el parto, y tenerlo en cuenta como diagnóstico diferencial. Es de vital importancia tener un manejo multidisciplinario compuesto por ginecoobstetra, internista, neumólogo y neonatólogo, incluido el apoyo por una unidad de cuidado intensivo para evitar complicaciones materno-perinatales que se puedan asociar al neumotórax espontáneo.

https://doi.org/10.24875/rechog.22000046

Predictors of poor outcomes in young non-comorbid patients with COVID-19
Facebook Twitter

Outras redes sociais
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Outras redes

Métricas
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

Martínez-Guerra, Bernardo A.

; Medrano-Borromeo, Carla

; González-Lara, María F.

; Román-Montes, Carla M.

; Tamez-Torres, Karla M.

; Rajme-López, Sandra

; Salgado-Guízar, Karla D.

; Juárez-Menéndez, Noe A.

; Ramos-Cervantes, Pilar

; Ruiz-Palacios, Guillermo M.

; Ponce-de-León, Alfredo

; Sifuentes-Osornio, José

Revista de investigación clínica

Métricas do periódico
- Sobre o periódico
- SciELO Analytics

Out 2022, Volume 74 Nº 5 Páginas 268 - 275

Resumo: En | Texto: En | PDF: En

ABSTRACT Background: Prognostic factors in previously healthy young patients with COVID-19 remained understudied. Objective: The objective of the study was to identify factors associated with in-hospital death or need for invasive mechanical ventilation (IMV) in young (aged ≤ 65 years) and previously healthy patients with COVID-19. Methods: We conducted a prospective cohort study that included patients admitted with COVID-19. The primary outcome was in-hospital death/need for IMV. Secondary outcomes included need for IMV during follow-up, days on IMV, length of stay (LOS), hospital-acquired pneumonia/ventilator-associated pneumonia (HAP/VAP), and pulmonary embolism (PE). Bivariate and multivariate analyses were performed. Results: Among 92 patients, primary outcome occurred in 16 (17%), death in 12 (13%), need for IMV in 16 (17%), HAP/VAP in 7 (8%), and PE in 2 (2%). Median LOS and IMV duration were 7 and 12 days, respectively. Independent associations were found between the primary outcome and male sex (Adjusted odds ratio [aOR] 7.1, 95%CI 1.1-46.0, p < 0.05), D-dimer levels > 1000ng/mL (aOR 9.0, 95%CI 1.6-49.1, p < 0.05), and RT-PCR Ct-value ≤ 24 on initial swab samples (aOR 14.3, 95%CI 2.0-101.5, p < 0.01). Conclusions: In young and non-comorbid COVID-19 patients, male sex, higher levels of D-dimer, and low SARS-CoV-2 RT-PCR Ct-value on an initial nasopharyngeal swab were independently associated with increased in-hospital mortality or need for IMV.

https://doi.org/10.24875/ric.22000162

Comparación de los resultados funcionales post operatorios en enucleación prostática con láser holmio, fotovaporización prostática con láser verde y resección transuretral de próstata en el tratamiento de la hiperplasia prostática obstructiva
Facebook Twitter

Outras redes sociais
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Outras redes

Métricas
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

Cruz-Ordoñez, Sandra Xochiquetzal

; Chein-Vázquez, María Fernanda

; Victorio-Vargas, Omar Dimas

; Cervantes-Palma, César

; Lemus-Hernández, Luis Alberto

; Toledo-Díaz, Mario Alberto

; Torres-Gómez, Jesús Javier

; Bravo-Castro, Edgar Iván

; Díaz-Gómez, Cristóbal

; Martínez-Alonso, Iván Azael

; Campos-Salcedo, José Gadú

Revista mexicana de urología

Métricas do periódico
- Sobre o periódico
- SciELO Analytics

Jun 2022, Volume 82 Nº 3 elocation e07

Resumo: En Es | Texto: En Es | PDF: En | PDF: Es

Abstract Objective: To compare the functional results in patients undergoing transurethral resection of the prostate (TURP), photovaporization of the prostate with GreenLight ® laser (FTV) and prostate enucleation with Holmium laser (HOLEP), for the treatment of benign prostatic obstruction at the Central Military Hospital. Material and methods: The international index of prostate symptomatology questionnaire (IPSS), Uroflowmetry (Qmax), pre and post void ultrasonography (PVR) were applied to patients undergoing TURP, VTF and HOLEP pre and postoperatory from January 2018 to March 2019. Shapiro-Wilks tests were analyzed for quantitative variables; parametric behavioral data were analyzed with ANOVA tests, and non-parametric data were analyzed with Mann-Whitney and Kruskal-Wallis U tests. GraphPad PRISM v7.0 statistical package was used. Results: 46 patients underwent to TURP, 62 to HOLEP and 17 to VFT were evaluated, removing those who did not achieve complete postoperative follow-up; describing the demographic characteristics, the most frequent comorbidities and the parameters evaluated preoperatively. At follow-up, HOLEP was slightly better than FTV or TURP; without finding statistical significance between the groups, observing an important improvement in the reference values of IPSS, Qmax and PVR after surgery in all populations. Conclusions: No superiority of any technique was proven in short-term postoperative functional results, so we propose to perform long-term studies, considering adding trans and postoperative parameters in order to demonstrate superiority of these techniques.

Resumen Objetivo: Comparar los resultados funcionales en pacientes operados de resección transuretral de próstata (RTUP), fotovaporización prostática con láser GreenLight ® (FTV) y enucleación prostática con láser Holmio (HOLEP), en el tratamiento de la obstrucción prostática benigna en el Hospital Central Militar. Material y métodos: Se aplicó cuestionario de índice internacional de sintomatología prostática (IPSS), Uroflujometría (Qmax), ultrasonografía vesical pre y postmiccional (PVR) a los pacientes llevados a RTUP, FTV y HOLEP de manera pre y post operatoria de enero del 2018 a marzo del 2019. Se analizaron las pruebas descriptivas y de normalidad de Shapiro-Wilks para las variables cuantitativas; los datos de comportamiento paramétrico se analizaron con pruebas de ANOVA, y los no paramétricos se analizaron con pruebas de U de Mann-Whitney y Kruskal-Wallis. Se utilizó paquete estadístico GraphPad PRISM v7.0. Resultados: Se evaluaron 46 pacientes de RTUP, 62 de HOLEP y 17 de FTV, eliminando aquellos que no lograron seguimiento postoperatorio completo; describiendo las características demográficas, las comorbilidades más frecuentes y los parámetros evaluados de manera preoperatoria. En el seguimiento, HOLEP fue ligeramente mejor que FTV o RTUP; sin encontrar significancia estadística entre los grupos, observando mejoría marcada de los valores de referencia de IPSS, Qmax y PVR pre y post operatorios en todas las poblaciones. Conclusiones: No se comprobó superioridad de alguna de las técnicas en cuanto a resultados funcionales postoperatorios a corto plazo, por lo que se propone realizar estudios a largo plazo, considerando agregar parámetros trans y postoperatorios a fin de demostrar superioridad de estas técnicas.

https://doi.org/10.48193/revistamexicanadeurologa.v82i3.743

Recomendaciones de práctica clínica: diagnóstico de osteomielitis en pie diabético
Facebook Twitter

Outras redes sociais
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Outras redes

Métricas
- SciELO Analytics

Carro, Gabriela Verónica

; Saurral, Rubén Nicolás

; Méndez, Elizabet Gladys

; Dituro, Claudio Fabián

; Varela, Cristina

; David, Raúl Alejandro

; Witman, Érica Lorena

; Torres, Julio Cesar

; Iluminati, Gabriela Silvana

; Casen, María Alejandra

; Alterini, Pablo

; Losada, María Victoria Dicatarina

; Kremer Sendros, Sandra Aixa

; Issa, Claudia

; Badías, Florencia

; Braver, José Daniel

; Romero, Elida

; Vega, Walter Agustín

; Carrió, Luisa Mabel

Revista de la Sociedad Argentina de Diabetes

Métricas do periódico
- Sobre o periódico
- SciELO Analytics

Mai 2022, Volume 56 Supl. 1 Páginas 36 - 39

Resumo: Es En | Texto: Es En | PDF: Es | PDF: En

Resumen La osteomielitis (OM) es una complicación de las úlceras en pie diabético que habitualmente es subdiagnosticada y tratada en forma tardía e inadecuada. La demora en el tratamiento de estos pacientes aumenta el riesgo de amputación. En esta revisión, se analiza la bibliografía actual acerca del diagnóstico de OM y se realizan recomendaciones en base a la misma, y a las características de los pacientes, los insumos y las posibilidades en nuestro medio.

Abstract Diabetic foot osteomyelitis (OM) is a diabetic foot ulcer complication. Usually, it is misdiagnosed and the treatment is delayed and inadequate. Delaying the treatment of these patients rises the risk of amputation. In this revision, current bibliography about this topic is updated and clinical practice recommendations are done, based on the publications and adapted to the characteristics of our country.

Effect of Tocilizumab in Mortality among Patients with Severe and Critical Covid-19: Experience in a Third-Level Medical Center
Facebook Twitter

Outras redes sociais
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Outras redes

Métricas
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

Martínez-Guerra, Bernardo A.

; de-León-Cividanes, Nereyda A.

; Tamez-Torres, Karla M.

; Román-Montes, Carla M.

; Rajme-López, Sandra

; Ortiz-Brizuela, Edgar

; Aguilar-Salinas, Carlos A.

; Sierra-Madero, Juan

; Sifuentes-Osornio, José

; Ponce-de-León, Alfredo

; González-Lara, María F.

Revista de investigación clínica

Métricas do periódico
- Sobre o periódico
- SciELO Analytics

Fev 2022, Volume 74 Nº 1 Páginas 40 - 50

Resumo: En | Texto: En | PDF: En

ABSTRACT Background: Trials evaluating safety and efficacy of tocilizumab in coronavirus disease 19 (COVID-19) show contradictory results. Objective: The objective of the study was to evaluate the effect of tocilizumab in hospital mortality among patients with severe COVID-19 in a third-level medical center. Methods: This prospective cohort study included patients with severe and critical COVID-19. Primary outcome was death during hospitalization. Secondary outcomes included invasive mechanical ventilation (IMV), days on IMV, ventilator-free days (VFDs), length of hospital stay (LOS), and development of hospital-acquired infections (HAIs). Bivariate, multivariate, and propensity score matching analysis were performed. Results: During the study period, 99/794 (12%) patients received tocilizumab. Male patients, health care workers, and patients with increased inflammatory markers received tocilizumab more frequently. No difference in hospital mortality was observed between groups (34% vs. 34%, p = 0.98). Tocilizumab was not independently associated with mortality. No significant treatment effects were observed in propensity score analysis. IMV was more frequent (46% vs. 11%, p < 0.01) and LOS was longer (12 vs. 7 days, p < 0.01) in the tocilizumab group, reflecting increased severity. Although HAIs were more frequent in the tocilizumab group (22% vs. 10%, p < 0.01), no difference was seen after adjusting for IMV (38% vs. 40%, p = 0.86). Conclusions: In our study, tocilizumab was not associated with decreased hospital mortality among patients with severe COVID-19.

https://doi.org/10.24875/ric.21000404 27 downloads

10.

Guidelines on COVID-19 vaccination in patients with immune-mediated rheumatic diseases: a Brazilian Society of Rheumatology task force
Facebook Twitter

Outras redes sociais
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Outras redes

Métricas
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

Tavares, Anna Carolina Faria Moreira Gomes

; Melo, Ana Karla Guedes de

; Cruz, Vítor Alves

; Souza, Viviane Angelina de

; Carvalho, Joana Starling de

; Machado, Ketty Lysie Libardi Lira

; Valadares, Lilian David de Azevedo

; Reis Neto, Edgard Torres dos

; Rezende, Rodrigo Poubel Vieira de

; Guimarães, Maria Fernanda Brandão de Resende

; Ferreira, Gilda Aparecida

; Braz, Alessandra de Sousa

; Vieira, Rejane Maria Rodrigues de Abreu

; Pinheiro, Marcelo de Medeiros

; Ribeiro, Sandra Lúcia Euzébio

; Bica, Blanca Elena Gomes Rios

; Baptista, Kátia Lino

; Costa, Izaias Pereira da

; Marques, Claudia Diniz Lopes

; Lopes, Maria Lúcia Lemos

; Martinez, José Eduardo

; Giorgi, Rina Dalva Neubarth

; Mota, Lícia Maria Henrique da

; Loures, Marcos Antônio Araújo da Rocha

; Paiva, Eduardo dos Santos

; Monticielo, Odirlei André

; Xavier, Ricardo Machado

; Kakehasi, Adriana Maria

; Pileggi, Gecilmara Cristina Salviato

Advances in Rheumatology

Métricas do periódico
- Sobre o periódico
- SciELO Analytics

2022, Volume 62 elocation 3

Resumo: En | Texto: En | PDF: En

Abstract Objective: To provide guidelines on the coronavirus disease 2019 (COVID-19) vaccination in patients with immune-mediated rheumatic diseases (IMRD) to rheumatologists considering specific scenarios of the daily practice based on the shared-making decision (SMD) process. Methods: A task force was constituted by 24 rheumatologists (panel members), with clinical and research expertise in immunizations and infectious diseases in immunocompromised patients, endorsed by the Brazilian Society of Rheumatology (BSR), to develop guidelines for COVID-19 vaccination in patients with IMRD. A consensus was built through the Delphi method and involved four rounds of anonymous voting, where five options were used to determine the level of agreement (LOA), based on the Likert Scale: (1) strongly disagree; (2) disagree, (3) neither agree nor disagree (neutral); (4) agree; and (5) strongly agree. Nineteen questions were addressed and discussed via teleconference to formulate the answers. In order to identify the relevant data on COVID-19 vaccines, a search with standardized descriptors and synonyms was performed on September 10th, 2021, of the MEDLINE, EMBASE, Cochrane Central Register of Controlled Trials, ClinicalTrials.gov, and LILACS to identify studies of interest. We used the Newcastle–Ottawa Scale to assess the quality of nonrandomized studies. Results: All the nineteen questions-answers (Q&A) were approved by the BSR Task Force with more than 80% of panelists voting options 4—agree—and 5—strongly agree—, and a consensus was reached. These Guidelines were focused in SMD on the most appropriate timing for IMRD patients to get vaccinated to reach the adequate covid-19 vaccination response. Conclusion: These guidelines were developed by a BSR Task Force with a high LOA among panelists, based on the literature review of published studies and expert opinion for COVID-19 vaccination in IMRD patients. Noteworthy, in the pandemic period, up to the time of the review and the consensus process for this document, high-quality evidence was scarce. Thus, it is not a substitute for clinical judgment.

https://doi.org/10.1186/s42358-022-00234-7

11.

Causas del hidrops fetal: experiencia en un hospital obstétrico del Occidente de México
Facebook Twitter

Outras redes sociais
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Outras redes

Métricas
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

Becerra-Solano, Luis Eduardo

; Medina-Castellanos, Marcela

; Oseguera-Torres, Luis Fernando

; Mendoza-Ruvalcaba, Sandra del Carmen

; Domínguez-Quezada, María Guadalupe

; García-Ortiz, José Elías

Ginecología y obstetricia de México

Métricas do periódico
- Sobre o periódico
- SciELO Analytics

2022, Volume 90 Nº 7 Páginas 579 - 589

Resumo: En Es | Texto: En Es | PDF: En | PDF: Es

Abstract OBJECTIVE: To identify the causes of nonimmune fetal hydrops fetalis in an obstetric referral hospital in Western Mexico. MATERIALS AND METHODS: Case series study, with non-probabilistic sampling by convenience, carried out from October 2014 to September 2015 which included patients (between 15 and 38 weeks of pregnancy), of legal age (in cases of minors, informed consent was requested from parents or guardians), with a diagnosis of fetal hydrops fetalis by obstetric ultrasound. For statistical analysis, an Excel database was generated and descriptive statistics were applied. RESULTS: Thirty-three pregnant women were included, in whom non-immune fetal hydrops fetalis was the most frequent (94%) and idiopathic was the most common cause (n = 10), followed by inborn errors of metabolism, chromosomal and cardiac alterations (n = 6 each). This was followed by hematologic (n = 4), lymphatic and syndromic causes (n = 3 each), and infectious and tumor causes (n = 1 each). In this study, inborn errors of metabolism (specifically Sly syndrome) had a higher frequency than that reported in the literature. CONCLUSIONS: Inborn errors of metabolism, chromosomal and cardiac abnormalities were the second most frequent cause of nonimmune fetal hydrops. It is suggested that metabolic causes be taken into account in the diagnostic approach to fetal hydrops, especially for the establishment of early treatment.

Resumen OBJETIVO: Identificar las causas de hidrops fetal no inmunitario en un hospital obstétrico de referencia del Occidente de México. MATERIALES Y MÉTODOS: Estudio de serie de casos, con un muestreo no probabilístico por conveniencia, llevado a cabo de octubre de 2014 a septiembre de 2015 al que se incluyeron pacientes (entre las 15 y 38 semanas de embarazo), mayores de edad (en casos de menores de edad se solicitó consentimiento informado a los padres o tutores), con diagnóstico de hidrops fetal por ultrasonido obstétrico. Para el análisis estadístico se generó una base de datos en Excel y se aplicó estadística descriptiva. RESULTADOS: Se reunieron 33 embarazadas en quienes el hidrops fetal no inmunitario fue el más frecuente (n = 31) y la causa idiopática más común (n = 10) seguida por errores innatos del metabolismo, alteraciones cromosómicas y cardiacas (n = 6 de cada una). Posteriormente, las causas hematológicas (n = 4), linfáticas y sindrómicas (n = 3 de cada una), y las infecciosas y tumorales (n = 1 de cada una). En este estudio los errores innatos del metabolismo (específicamente síndrome Sly) tuvieron una frecuencia superior a la referida en la bibliografía. CONCLUSIONES: Los errores innatos del metabolismo, las anomalías cromosómicas y cardiacas fueron la segunda causa más frecuente de hidrops fetal no inmunitario. Se sugiere tener en cuenta las causas metabólicas en el enfoque diagnóstico del hidrops fetal, sobre todo para el establecimiento del tratamiento temprano.

https://doi.org/10.24245/gom.v90i7.6623 13 downloads

12.

Comparación entre el ultrasonido y la resonancia magnética en la evaluación de defectos estructurales fetales del sistema nervioso central
Facebook Twitter

Outras redes sociais
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Outras redes

Métricas
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

Velazquez-Torres, Berenice

; Portugal-Cruz, Christian E

; García-Moreno, Carla María

; Gallardo-Gaona, Juan Manuel

; Rodríguez-Sibaja, María José

; Acevedo-Gallegos, Sandra

Ginecología y obstetricia de México

Métricas do periódico
- Sobre o periódico
- SciELO Analytics

2022, Volume 90 Nº 2 Páginas 148 - 155

Resumo: En Es | Texto: En Es | PDF: En | PDF: Es

Abstract : OBJECTIVE: To describe and compare all cases with central nervous system defects evaluated prenatally with structural ultrasound and magnetic resonance imaging. MATERIALS AND METHODS: Case series, retrolective, based on the records of the Structural Defects Clinic. Inclusion criteria: fetuses with central nervous system defects. Structural revisions were collected from the clinical record and reported MRI findings. Comparisons between the findings of the two methods were established, considering the final diagnoses established after birth. RESULTS: Fifty-eight cases were analyzed; in 34 cases the MRI and ultrasound findings were the same. In 12 cases the MRI provided additional information and in another 12 cases the diagnosis changed. Neural tube defects and midline malformations had the highest incidence (n = 13 of each). Ultrasound had the highest failure rate for cortical formation anomalies and destructive lesions (29 and 33, respectively). CONCLUSIONS: Prenatal MRI is a complementary tool to ultrasound that is useful in the evaluation of central nervous system abnormalities, primarily cortical alterations. Ultrasound and MRI have strengths and limitations; each performs better in different aspects of the structural evaluation of the central nervous system. So far there is insufficient evidence to pinpoint the superiority of one over the other.

Resumen: OBJETIVO: Describir y comparar todos los casos con defectos en el sistema nervioso central evaluados prenatalmente con ultrasonido estructural y con resonancia magnética. MATERIALES Y METODOS: Serie de casos, retrolectiva, basada en los registros de la Clínica de Defectos Estructurales. Criterios de inclusión: fetos con defectos en el sistema nervioso central. Las revisiones estructurales se recolectaron del expediente clínico y de los hallazgos reportados de la resonancia magnética. Se establecieron las comparaciones entre los hallazgos de los dos métodos, tomando en cuenta los diagnósticos finales establecidos después del nacimiento. RESULTADOS: Se analizaron 58 casos; en 34 los hallazgos en la resonancia magnética y en el ultrasonido fueron exactamente los mismos. En 12 casos la resonancia magnética aportó información adicional y en otros 12 casos cambió el diagnóstico. Los defectos del tubo neural y las malformaciones de la línea media fueron los de mayor incidencia (n = 13 de cada uno). El ultrasonido tuvo la mayor tasa de falla para las anomalías de la formación cortical y las lesiones destructivas (29 y 33, respectivamente). CONCLUSIONES: La resonancia magnética prenatal es una herramienta complementaria al ultrasonido que resulta útil en la evaluación de las anomalías del sistema nervioso central, principalmente en las alteraciones corticales. El ultrasonido y la resonancia tienen fortalezas y limitaciones; cada uno se desempeña mejor en distintos aspectos de la evaluación estructural del sistema nervioso central. Hasta el momento no existe evidencia suficiente para precisar la superioridad de uno en comparación con el otro.

https://doi.org/10.24245/gom.v90i2.6969 148 downloads

13.

Factors associated with hospitalizations for Covid-19 in patients with rheumatoid arthritis: data from the Reumacov Brazil registry
Facebook Twitter

Outras redes sociais
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Outras redes

Métricas
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

Gomides, Ana Paula Monteiro

; Albuquerque, Cleandro Pires de

; Mota, Licia Maria Henrique da

; Devidé, Guilherme

; Dias, Laiza Hombre

; Duarte, Angela Luzia Branco Pinto

; Giovelli, Raquel Altoé

; Karnopp, Thais Evelyn

; Lima, Hugo Deleon de

; Marinho, Adriana

; Oliveira, Marianne Schrader de

; Omura, Felipe

; Ranzolin, Aline

; Resende, Gustavo

; Ribeiro, Francinne Machado

; Ribeiro, Sandra Lúcia Euzébio

; Sacilotto, Nathália de Carvalho

; Santos, Wander Gonzaga dos

; Shinjo, Samuel Katsuyuki

; Studart, Samia Araujo de Sousa

; Teixeira, Flávia Patricia Sena

; Yazbek, Michel Alexandre

; Ferreira, Gilda Aparecida

; Monticielo, Odirlei A.

; Paiva, Eduardo

; Pileggi, Gecilmara Cristina Salviato

; Reis Neto, Edgard Torres dos

; Pinheiro, Marcelo de Medeiros

; Marques, Claudia D. L.

Advances in Rheumatology

Métricas do periódico
- Sobre o periódico
- SciELO Analytics

2022, Volume 62 elocation 13

Resumo: En | Texto: En | PDF: En

Abstract Background: Patients using immunosuppressive drugs may have unfavorable results after infections. However, there is a lack of information regarding COVID 19 in these patients, especially in patients with rheumatoid arthritis (RA). Therefore, the aim of this study was to evaluate the risk factors associated with COVID 19 hospitalizations in patients with RA. Methods: This multicenter, prospective cohort study is within the ReumaCoV Brazil registry and included 489 patients with RA. In this context, 269 patients who tested positive for COVID 19 were compared to 220 patients who tested negative for COVID 19 (control group). All patient data were collected from the Research Electronic Data Capture database. Results: The participants were predominantly female (90.6%) with a mean age of 53 ±12 years. Of the patients with COVID 19, 54 (20.1%) required hospitalization. After multiple adjustments, the final regression model showed that heart disease (OR =4.61, 95% CI 1.06–20.02. P < 0.001) and current use of glucocorticoids (OR =20.66, 95% CI 3.09–138. P < 0.002) were the risk factors associated with hospitalization. In addition, anosmia was associated with a lower chance of hospitalization (OR =0.26; 95% CI 0.10–0.67, P < 0.005). Conclusion: Our results demonstrated that heart disease and the use of glucocorticoids were associated with a higher number of hospital admissions for COVID 19 in patients with RA. Trial registration: Brazilian Registry of Clinical Trials RBR 33YTQC.

https://doi.org/10.1186/s42358-022-00244-5

14.

Adolescents and young adults infected by the Human Papillomavirus (HPV): vulnerabilities and feelings experienced
Facebook Twitter

Outras redes sociais
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Outras redes

Métricas
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

Reis, Maria Carolina Oliveira

; Martins, Adenilda Lima Lopes

; Carvalho, Rosely Cabral de

; Moreira, Rita de Cássia Rocha

; Peixoto, Marcelo Torres

; Souza, Sandra Ely Barbosa de

Revista Gaúcha de Enfermagem

Métricas do periódico
- Sobre o periódico
- SciELO Analytics

2022, Volume 43 elocation e20210228

Resumo: Pt En Es | Texto: Pt En Es | PDF: Pt | PDF: En | PDF: Es

RESUMO Objetivo: Conhecer as vulnerabilidades vivenciadas por adolescentes e adultas jovens infectadas pelo Papilomavírus Humano atendidas em um centro de referência em Feira de Santana - Bahia. Método: Estudo qualitativo, realizado entrevista semiestruturada com 20 adolescentes e adultas jovens, no período de novembro de 2020 a fevereiro de 2021. Para análise dos dados, utilizaram-se a Análise de Conteúdo proposta por Bardin e o software Iramuteq. Resultados: A descoberta da infecção realça a incompreensão sobre o adoecimento, o medo, o desespero e a culpa, dimensões individuais e coletivas que apontam para o baixo conhecimento sobre o Papilomavírus Humano. Considerações finais: Faz-se necessário a implementação de políticas públicas para minimizar os riscos, pelo conhecimento e enfrentamento às infecções sexualmente transmissíveis, bem como estratégias de promoção da saúde e decisões compartilhadas para o processo de mudança de comportamento em adolescentes e adultas jovens.

ABSTRACT Objective: To know the vulnerabilities experienced by adolescents and young adults infected by the Human Papillomavirus attended at a reference center in Feira de Santana - Bahia. Method: Qualitative study, carried out with a semi-structured interview with 20 adolescents and young adults, from November 2020 to February 2021. For data analysis, the Content Analysis proposed by Bardin and the software Iramuteq were used. Results: The discovery of the infection highlights the misunderstanding about illness, fear, despair and guilt, individual and collective dimensions that point to little knowledge about the Human Papillomavirus. Final considerations: It is necessary to implement public policies to minimize risks, through knowledge and confrontation of sexually transmitted infections, as well as health promotion strategies and shared decisions for the process of behavior change in adolescents and young adults.

RESUMEN Objetivo: Conocer las vulnerabilidades vividas por adolescentes y adultos jóvenes infectados por el Virus del Papiloma Humano atendidos en un centro de referencia en Feira de Santana - Bahia. Método: Estudio cualitativo, realizado con entrevista semiestructurada a 20 adolescentes y adultos jóvenes, de noviembre de 2020 a febrero de 2021. Para el análisis de datos se utilizó el Análisis de Contenido propuesto por Bardin y el software Iramuteq. Resultados: El descubrimiento de la infección destaca la incomprensión sobre la enfermedad, el miedo, la desesperación y la culpa, dimensiones individuales y colectivas que apuntan al bajo conocimiento sobre el Virus del Papiloma Humano. Consideraciones finales: Es necesario implementar políticas públicas para la minimización de riesgos, a través del conocimiento y enfrentamiento de las infecciones de transmisión sexual, así como estrategias de promoción de la salud y decisiones compartidas para el proceso de cambio de comportamiento en adolescentes y adultos jóvenes.

https://doi.org/10.1590/1983-1447.2022.20210228.en

15.

O papel da imagem corporal positiva na qualidade de vida de pessoas com insuficiência renal crónica
Facebook Twitter

Outras redes sociais
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Outras redes

Métricas
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

Cunha, Margarida S.

; Vieira, Filipa E.

; Cepeda, Rita S.

; Torres, Sandra C.

; Barbosa, Maria Raquel

Psicologia

Métricas do periódico
- Sobre o periódico
- SciELO Analytics

Dez 2021, Volume 35 Nº 2 Páginas 63 - 78

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

Resumo Este estudo pretende explorar o papel da imagem corporal positiva (ICP) na qualidade de vida (QdV) de pessoas com insuficiência renal crónica (IRC). A recolha de dados foi efetuada através de instrumentos de autorrelato que permitiram a contemplação das variáveis sociodemográficas, de algumas dimensões da ICP e da QdV, num grupo clínico (n = 46; M = 59,8 anos) e num grupo não clínico (n = 49; M = 55,1 anos) de participantes. Percebeu-se que as várias dimensões da ICP se associam com os diferentes domínios da QdV em ambos os grupos. As mulheres revelaram níveis superiores nas dimensões da aceitação do corpo pelos outros e no autocuidado, comparativamente aos homens. Por último, destaca-se o papel da apreciação da funcionalidade corporal como um importante preditor da QdV. Salienta-se a relevância de se intervir na ICP pelo impacto positivo que pode ter na QdV desta população.

Abstract This study aims to explore the role of positive body image (PBI) in the quality of life (QoL) of people with chronic renal failure (CRF). Data collection was performed using self-report instruments that allowed sociodemographic variables, some dimensions of PBI and QoL, in a clinical group (n = 46; M = 59.8 years) and in a non-clinical group (n = 49; M = 55.1 years) of participants. It was founded a positive association between PBI dimensions and the different domains of QoL in both groups. Women showed higher levels in the dimensions of body acceptance by others and self-care, compared to men. Finally, the results underlined the role of body functionality appreciation has as an important predictor of QoL. The importance of intervening in PCI is highlighted due to the positive impact it can have on the QoL of this population.

https://doi.org/10.17575/psicologia.v35i2.1739 25 downloads

Exibindo

itens por página

Página de 7 Próxima

Selecione um ou mais resultados

Todos Ordem alfabética

Resultados

Gráfico comparativo Download CSV

Visualizar estatísticas de

Enviar resultado

E-mail do(s) destinatários*

Utilize ; (ponto e vírgula) para mais de um e-mail.

Enviar por e-mail

Esta página

Registros selecionados

Todos os registros (max. 300)

Alterar remetente, assunto e comentários

Seu email

Assunto

Comentários

Alterar remetente, assunto e comentários

Exportar resultados

Formato de exportação:

RIS (para EndNote, ProCite, Reference Manager, RefWorks, Citavi, etc.)

BibTeX

Citação

CSV (para Excel, etc)

Exportar:

Esta página

Itens selecionados

Todos os registros (max. 2000)

Mostrar mais

Sem resultados

Não foram encontrados documentos para sua pesquisa

Glossário e ajuda para busca

Você pode enriquecer sua busca de uma forma muito simples. Use os índices de pesquisa combinados com os conectores (AND ou OR) e especifique cada vez mais sua busca.

Por exemplo, se você deseja buscar artigos sobre
casos de dengue no Brasil em 2015, use:
ti:dengue and publication_year:2015 and aff_country:Brasil

Veja abaixo a lista completa de índices de pesquisa que podem ser usados:

Cód. do Índice	Elemento
ti	título do artigo
au	autor
kw	palavras-chave do artigo
subject	assunto (palavras do título, resumo e palavras-chave)
ab	resumo
ta	título abreviado da revista (ex. Cad. Saúde Pública)
journal_title	título completo da revista (ex. Cadernos de Saúde Pública)
la	código do idioma da publicação (ex. pt - Português, es - Espanhol)
type	tipo do documento
pid	identificador da publicação
publication_year	ano de publicação do artigo
sponsor	financiador
aff_country	código do país de afiliação do autor
aff_institution	instituição de afiliação do autor
volume	volume do artigo
issue	número do artigo
elocation	elocation
doi	número DOI
issn	ISSN da revista
in	código da coleção SciELO (ex. scl - Brasil, col - Colômbia)
use_license	código da licença de uso do artigo

SciELO - Scientific Electronic Library Online
Rua Dr. Diogo de Faria, 1087 – 9º andar – Vila Clementino 04037-003 São Paulo/SP - Brasil
Email: scielo@scielo.org

Todo o conteúdo de www.scielo.org, exceto onde está identificado, está licenciado sob uma Licença Creative Commons.
saiba mais »